2. Gene
  3. Mul1 - mitochondrial ubiquitin ligase activator of NFKB 1 Gene

Mul1 - mitochondrial ubiquitin ligase activator of NFKB 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Gide; 0610009K11Rik

Gene ID: 68350 | Gene type: protein coding

About Mul1

Summary

Predicted to enable several functions, including p53 binding activity; ubiquitin protein Ligase binding activity; and ubiquitin-like protein transferase activity. Involved in several processes, including positive regulation of Autophagy of mitochondrion in response to mitochondrial depolarization; positive regulation of dendrite extension; and regulation of protein stability. Located in mitochondrion. Orthologous to human MUL1 (mitochondrial E3 ubiquitin protein Ligase 1). [provided by Alliance of Genome Resources, Apr 2022]

Mul1 Products(1)

mRNA Protein Name
NM_026689.3 NP_080965.2 mitochondrial ubiquitin ligase activator of NFKB 1
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of dendrite extension IGI
IGI: Inferred from genetic interaction
24898855 MGI
involved in positive regulation of dendrite extension IMP
IMP: Inferred from mutant phenotype
24898855 MGI
involved in positive regulation of type 2 mitophagy IMP
IMP: Inferred from mutant phenotype
24709290 MGI
involved in regulation of mitochondrial membrane potential IGI
IGI: Inferred from genetic interaction
24898855 MGI
involved in regulation of protein stability IMP
IMP: Inferred from mutant phenotype
24898855 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mitochondrial ubiquitin ligase activator of NFKB 1

E3 ubiquitin ligase

E3 ubiquitin-protein ligase MUL1

RING-type E3 ubiquitin transferase NFKB 1

growth inhibition and death E3 ligase

protein Hades

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08850 MUL1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21381 Mul1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mul1 NCBI NCBI:79594