2. Gene
  3. Sdhb - succinate dehydrogenase complex, subunit B, iron sulfur (Ip) Gene

Sdhb - succinate dehydrogenase complex, subunit B, iron sulfur (Ip) Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 0710008N11Rik

Gene ID: 67680 | Gene type: protein coding

About Sdhb

Summary

Predicted to enable Succinate Dehydrogenase (ubiquinone) activity. Predicted to be involved in aerobic respiration; respiratory electron transport chain; and succinate metabolic process. Predicted to act upstream of or within tricarboxylic acid cycle. Located in mitochondrion. Part of mitochondrial respiratory chain complex II, Succinate Dehydrogenase complex (ubiquinone). Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in Carney-Stratakis syndrome; gastrointestinal stromal tumor; mitochondrial complex II deficiency; paraganglioma; and pheochromocytoma. Orthologous to human SDHB (Succinate Dehydrogenase complex iron sulfur subunit B). [provided by Alliance of Genome Resources, Apr 2022]

Sdhb Products(2)

mRNA Protein Name
NM_001355515.1 NP_001342444.1 succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial isoform 2
NM_023374.4 NP_075863.2 succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial isoform 1 precursor
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in mitochondrion IDA
IDA: Inferred from direct assay
11829486 MGI
part of respiratory chain complex II (succinate dehydrogenase) IDA
IDA: Inferred from direct assay
16120479 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial

ip

iron-sulfur subunit of complex II

succinate dehydrogenase complex subunit B

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12593 SDHB Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-169281 Antiviral agent 61 Inhibitor / Unkown
HY-RS18259 Sdhb Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24738 Sdhb Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sdhb NCBI NCBI:6390