2. Gene
  3. Nr1i3 - nuclear receptor subfamily 1, group I, member 3 Gene

Nr1i3 - nuclear receptor subfamily 1, group I, member 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as CAR

Gene ID: 65035 | Gene type: protein coding

About Nr1i3

Summary

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and nuclear receptor activity. Involved in osteoblast differentiation. Located in cytoplasm and nucleus. Biomarker of cholestasis. Orthologous to human NR1I3 (nuclear receptor subfamily 1 group I member 3). [provided by Alliance of Genome Resources, Apr 2022]

Nr1i3 Products(4)

mRNA Protein Name
NM_001270838.1 NP_001257767.1 nuclear receptor subfamily 1 group I member 3 isoform 3
NM_001270839.1 NP_001257768.1 nuclear receptor subfamily 1 group I member 3 isoform 4
NM_001270840.1 NP_001257769.1 nuclear receptor subfamily 1 group I member 3 isoform 2
NM_022941.4 NP_075230.1 nuclear receptor subfamily 1 group I member 3 isoform 1
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in osteoblast differentiation IEP
IEP: Inferred from expression pattern
19702932 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nuclear receptor subfamily 1 group I member 3

constitutive androstane receptor

nuclear receptor constitutive active receptor

strain Fischer nuclear receptor (CAR)

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09535 NR1I3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20068 Nr1i3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26572 Nr1i3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nr1i3 NCBI NCBI:9970