2. Gene
  3. Clstn2 - calsyntenin 2 Gene

Clstn2 - calsyntenin 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Cs2; CSTN2; Cst-2; mKIAA4134; 2900042C18Rik

Gene ID: 64085 | Gene type: protein coding

About Clstn2

Summary

Predicted to enable calcium ion binding activity. Acts upstream of or within positive regulation of synapse assembly and positive regulation of synaptic transmission. Located in cell surface; postsynaptic density; and postsynaptic membrane. Is integral component of postsynaptic density membrane. Is active in glutamatergic synapse. Is expressed in several structures, including brain; ear; forelimb bud; heart; and paraxial mesenchyme. Orthologous to human CLSTN2 (calsyntenin 2). [provided by Alliance of Genome Resources, Apr 2022]

Clstn2 Products(2)

mRNA Protein Name
NM_001413406.1 NP_001400335.1 calsyntenin-2 isoform 2 precursor
NM_022319.3 NP_071714.2 calsyntenin-2 isoform 1 precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in associative learning IMP
IMP: Inferred from mutant phenotype
26171716 MGI
involved in inhibitory synapse assembly IMP
IMP: Inferred from mutant phenotype
26171716 MGI
acts upstream of or within positive regulation of synapse assembly IGI
IGI: Inferred from genetic interaction
24613359 MGI
acts upstream of or within positive regulation of synaptic transmission IGI
IGI: Inferred from genetic interaction
24613359 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cell surface IDA
IDA: Inferred from direct assay
24613359 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
12498782 MGI
located in postsynaptic density IDA
IDA: Inferred from direct assay
24613359 MGI
is active in postsynaptic density membrane IDA
IDA: Inferred from direct assay
12498782 MGI
located in postsynaptic membrane IDA
IDA: Inferred from direct assay
12498782 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

calsyntenin-2

alc-gamma

alcadein-gamma

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02841 CLSTN2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21107 Clstn2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27626 Clstn2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Clstn2 NCBI NCBI:64084