2. Gene
  3. Hspa2 - heat shock protein family A (Hsp70) member 2 Gene

Hspa2 - heat shock protein family A (Hsp70) member 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Hst70; Hspt70

Gene ID: 60460 | Gene type: protein coding

About Hspa2

Summary

Enables chaperone binding activity and Tau Protein binding activity. Predicted to be involved in several processes, including chaperone cofactor-dependent protein refolding; positive regulation of ATPase activity; and positive regulation of ATPase-coupled calcium transmembrane transporter activity. Predicted to act upstream of or within several processes, including male gamete generation; positive regulation of G2/M transition of mitotic cell cycle; and synaptonemal complex disassembly. Predicted to be located in cell surface; meiotic spindle; and nucleus. Predicted to be part of CatSper complex. Predicted to be active in cytosol; nucleus; and plasma membrane. Orthologous to human HSPA2 (heat shock protein family A (HSP70) member 2). [provided by Alliance of Genome Resources, Apr 2022]

Hspa2 Products(1)

mRNA Protein Name
NM_021863.3 NP_068635.1 heat shock-related 70 kDa protein 2
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
16518874 RGD
enables protein-folding chaperone binding IPI
IPI: Inferred from physical interaction
19228967 RGD
enables tau protein binding IPI
IPI: Inferred from physical interaction
19228967 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

heat shock-related 70 kDa protein 2

HST

heat shock 70kDa protein 2

heat shock protein 2

heat shock protein 70.2

heat shock protein alpha 2

heat shock protein family A member 2

testis-specific heat shock protein-related gene hst70

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-152153 GRP78-IN-3 Inhibitor 99.98% Unkown
HY-RS06427 HSPA2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20423 Hspa2 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25750 Hspa1b Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26932 Hspa2 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hspa2 NCBI NCBI:3306