2. Gene
  3. Smad5 - SMAD family member 5 Gene

Smad5 - SMAD family member 5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Madh5

Gene ID: 59328 | Gene type: protein coding

About Smad5

Summary

Predicted to enable several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; I-SMAD binding activity; and enzyme binding activity. Involved in Mullerian duct regression and ossification. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of heteromeric SMAD protein complex. Orthologous to human SMAD5 (Smad Family member 5). [provided by Alliance of Genome Resources, Apr 2022]

Smad5 Products(1)

mRNA Protein Name
NM_021692.1 NP_067724.1 mothers against decapentaplegic homolog 5
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in Mullerian duct regression IMP
IMP: Inferred from mutant phenotype
16687449 RGD
involved in ossification IEP
IEP: Inferred from expression pattern
11920662 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mothers against decapentaplegic homolog 5

MAD homolog 5

SMAD 5

SMAD, mothers against DPP homolog 5

mothers against DPP homolog 5

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13396 SMAD5 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20491 Smad5 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26999 Smad5 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Smad5 NCBI NCBI:4090
Mus musculus Smad5 NCBI NCBI:17129