Brinp1 - bone morphogenic protein/retinoic acid inducible neural specific 1 Gene

Mus musculus

Also known as Dbc1; BRINP; Fam5a; Dbccr1

Gene ID: 56710 | Gene type: protein coding

About Brinp1

Summary

Involved in cellular response to retinoic acid; negative regulation of mitotic cell cycle; and positive regulation of neuron differentiation. Acts upstream of or within several processes, including behavioral fear response; maternal behavior; and short-term memory. Predicted to be located in cytoplasm. Predicted to be active in dendrite; endoplasmic reticulum; and neuronal cell body. Is expressed in central nervous system; dorsal root ganglion; and submandibular gland primordium. Used to study attention deficit hyperactivity disorder and autism spectrum disorder. Orthologous to human BRINP1 (BMP/retinoic acid inducible neural specific 1). [provided by Alliance of Genome Resources, Apr 2022]

Brinp1 Products(1)

mRNA	Protein	Name
NM_019967.2	NP_064351.2	BMP/retinoic acid-inducible neural-specific protein 1 precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	25732823	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within behavioral fear response	IMP IMP: Inferred from mutant phenotype	24528488	MGI
involved in brain development	IMP IMP: Inferred from mutant phenotype	27042284	MGI
acts upstream of or within cell population proliferation	IMP IMP: Inferred from mutant phenotype	25732823	MGI
involved in cellular response to retinoic acid	IDA IDA: Inferred from direct assay	20025061	MGI
involved in central nervous system neuron development	IDA IDA: Inferred from direct assay	20025061	MGI
acts upstream of or within exploration behavior	IMP IMP: Inferred from mutant phenotype	27042284	MGI
acts upstream of or within gene expression	IMP IMP: Inferred from mutant phenotype	25732823	MGI
acts upstream of or within homeostasis of number of cells within a tissue	IMP IMP: Inferred from mutant phenotype	29960053	MGI
acts upstream of or within maternal behavior	IMP IMP: Inferred from mutant phenotype	27042284	MGI
involved in negative regulation of mitotic cell cycle	IDA IDA: Inferred from direct assay	20025061	MGI
acts upstream of or within negative regulation of neurogenesis	IMP IMP: Inferred from mutant phenotype	24528488	MGI
acts upstream of neurogenesis	IMP IMP: Inferred from mutant phenotype	24528488	MGI
acts upstream of or within proteasomal protein catabolic process	IMP IMP: Inferred from mutant phenotype	25732823	MGI
acts upstream of or within protein stabilization	IMP IMP: Inferred from mutant phenotype	25732823	MGI
acts upstream of or within short-term memory	IMP IMP: Inferred from mutant phenotype	27042284	MGI
acts upstream of or within social behavior	IMP IMP: Inferred from mutant phenotype	24528488	MGI
acts upstream of or within vocalization behavior	IMP IMP: Inferred from mutant phenotype	27042284	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
is active in glutamatergic synapse	IDA IDA: Inferred from direct assay	31171447	MGI
is active in synapse	IDA IDA: Inferred from direct assay	31171447	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

BMP/retinoic acid-inducible neural-specific protein 1

BMP/retinoic acid-inducible neural-specific protein (BRINP)	deleted in bladder cancer chromosome region candidate 1
deleted in bladder cancer protein 1 homolog

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01620	BRINP1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS21828	Brinp1 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Brinp1	NCBI	NCBI:1620

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