2. Gene
  3. ANGPTL3 - Angptl3 angiopoietin-like 3 Gene

ANGPTL3 - Angptl3 angiopoietin-like 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 502970 | Gene type: protein coding

About ANGPTL3

Summary

Predicted to enable growth factor activity; Integrin binding activity; and Phospholipase Inhibitor activity. Involved in response to hormone. Predicted to be located in Golgi apparatus; cell surface; and early endosome. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Human ortholog(s) of this gene implicated in familial hypobetalipoproteinemia 2. Orthologous to human ANGPTL3 (angiopoietin like 3). [provided by Alliance of Genome Resources, Apr 2022]

ANGPTL3 Products(3)

mRNA Protein Name
NM_001025065.2 NP_001020236.1 angiopoietin-related protein 3 isoform 2 precursor
NM_001399252.1 NP_001386181.1 angiopoietin-related protein 3 isoform 1 precursor
NM_001399253.1 NP_001386182.1 angiopoietin-related protein 3 isoform 3 precursor
Protein Preferred Names Protein Names

angiopoietin-related protein 3

Related Agents

Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-153497A Vupanorsen sodium Inhibitor 98.33% Phase 2
HY-153497 Vupanorsen Inhibitor 92.29% Phase 2

Orthologs Information

Species Symbol Source ID
Homo sapiens ANGPTL3 NCBI NCBI:27329
Macaca fascicularis ANGPTL3 NCBI NCBI:102136264
Mus musculus ANGPTL3 NCBI NCBI:30924