2. Gene
  3. Man1b1 - mannosidase, alpha, class 1B, member 1 Gene

Man1b1 - mannosidase, alpha, class 1B, member 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as ERMan1; RGD1563595

Gene ID: 499751 | Gene type: protein coding

About Man1b1

Summary

Predicted to enable mannosyl-oligosaccharide 1,2-alpha-mannosidase activity. Predicted to be involved in N-glycan processing; mannose trimming involved in glycoprotein ERAD pathway; and trimming of terminal mannose on B branch. Predicted to be located in cytoplasmic vesicle and endoplasmic reticulum quality control compartment. Predicted to be active in endoplasmic reticulum and membrane. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human MAN1B1 (mannosidase alpha class 1B member 1). [provided by Alliance of Genome Resources, Apr 2022]

Man1b1 Products(1)

mRNA Protein Name
NM_001109196.1 NP_001102666.1 endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase
Protein Preferred Names Protein Names

endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase

ER alpha-1,2-mannosidase

ER mannosidase 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08006 MAN1B1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19789 Man1b1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26285 Man1b1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Man1b1 NCBI NCBI:11253