2. Gene
  3. Dnmt3a - DNA methyltransferase 3 alpha Gene

Dnmt3a - DNA methyltransferase 3 alpha Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 444984 | Gene type: protein coding

About Dnmt3a

Summary

Enables chromatin binding activity. Involved in several processes, including cellular response to ethanol; hepatocyte apoptotic process; and response to vitamin A. Located in cytoplasm and nucleus. Used to study lung carcinoma and middle cerebral artery infarction. Biomarker of congenital heart disease; hepatocellular carcinoma; and prostatitis. Human ortholog(s) of this gene implicated in T-cell acute lymphoblastic leukemia; acute lymphoblastic leukemia; acute myeloid leukemia; myelodysplastic syndrome; and stomach Cancer. Orthologous to human DNMT3A (DNA Methyltransferase 3 alpha). [provided by Alliance of Genome Resources, Apr 2022]

Dnmt3a Products(2)

mRNA Protein Name
NM_001003957.1 NP_001003957.1 DNA (cytosine-5)-methyltransferase 3A isoform 2
NM_001003958.1 NP_001003958.1 DNA (cytosine-5)-methyltransferase 3A isoform 1
Protein Preferred Names Protein Names

DNA (cytosine-5)-methyltransferase 3A

DNA (cytosine-5-)-methyltransferase 3 alpha

DNA methyltransferase 3A

cysteine methyltransferase DNMT3A

Related Agents

Approval
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B2194 γ-Oryzanol Inhibitor 98.30% Unkown
Pre-clinical Phase
Bioactive Molecules (11)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-13962 SGI-1027 99.77% Unkown
HY-101925 CM-272 98.70% Unkown
HY-151136 DY-46-2 Inhibitor 99.32% Unkown
HY-144433 DNMT3A-IN-1 Inhibitor 99.94% Unkown
HY-124131 DS-437 Inhibitor 98.00% Unkown
HY-111544 EML741 Inhibitor / Unkown
HY-RS03911 DNMT3A Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-150025 (4aS,8aR)-NPD-001 / Unkown
HY-172217 DNMT1-IN-5 / Unkown
HY-RS16763 Dnmt3a Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS23203 Dnmt3a Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dnmt3a NCBI NCBI:1788