2. Gene
  3. Terc - telomerase RNA component Gene

Terc - telomerase RNA component Gene

  • Gene
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Tr

Gene ID: 378461 | Gene type: ncRNA

About Terc

Summary

Predicted to enable template for synthesis of G-rich strand of telomere DNA activity. Involved in negative regulation of cell differentiation. Predicted to be part of Telomerase holoenzyme complex. Human ortholog(s) of this gene implicated in autosomal dominant dyskeratosis congenita 1; cervix uteri carcinoma in situ; and prostate Cancer. Orthologous to human TERC (Telomerase RNA component). [provided by Alliance of Genome Resources, Apr 2022]

Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of cell differentiation IMP
IMP: Inferred from mutant phenotype
16424384 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-137817 BCH001 Inhibitor 98.83% Unkown
HY-RS16330 TERC Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17417 Terc Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23871 Terc Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Terc NCBI NCBI:7012
Canis familiaris Terc NCBI
Macaca fascicularis Terc NCBI
Mus musculus Terc NCBI NCBI:21748
Macaca mulatta Terc NCBI NCBI:100429884