2. Gene
  3. Gtf2i - general transcription factor II I Gene

Gtf2i - general transcription factor II I Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Gtf2ird1

Gene ID: 353256 | Gene type: protein coding

About Gtf2i

Summary

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II-specific DNA-binding transcription factor binding activity; and mitogen-activated protein kinase binding activity. Involved in negative regulation of cytosolic calcium ion concentration. Predicted to be located in cell projection; neuronal cell body; and nucleoplasm. Predicted to be active in nucleus. Orthologous to human GTF2I (general transcription factor IIi). [provided by Alliance of Genome Resources, Apr 2022]

Gtf2i Products(3)

mRNA Protein Name
NM_001001512.3 NP_001001512.2 general transcription factor II-I isoform 1
NM_001401209.1 NP_001388138.1 general transcription factor II-I isoform 2
NM_001401210.1 NP_001388139.1 general transcription factor II-I isoform 3
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of cytosolic calcium ion concentration IMP
IMP: Inferred from mutant phenotype
17023658 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

general transcription factor II-I

GTFII-I

TFII-I

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05903 GTF2I Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20950 Gtf2i Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27467 Gtf2i Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gtf2i NCBI NCBI:2969