2. Gene
  3. Dhps - deoxyhypusine synthase Gene

Dhps - deoxyhypusine synthase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Dhs

Gene ID: 330817 | Gene type: protein coding

About Dhps

Summary

Predicted to enable deoxyhypusine synthase activity and identical protein binding activity. Acts upstream of or within glucose homeostasis; peptidyl-lysine modification to peptidyl-hypusine; and positive regulation of T cell proliferation. Predicted to be active in cytoplasm. Orthologous to human DHPS (deoxyhypusine synthase). [provided by Alliance of Genome Resources, Apr 2022]

Dhps Products(1)

mRNA Protein Name
NM_001039514.1 NP_001034603.1 deoxyhypusine synthase
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables deoxyhypusine synthase activity IMP
IMP: Inferred from mutant phenotype
8697449 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within glucose homeostasis IMP
IMP: Inferred from mutant phenotype
24196968 MGI
acts upstream of or within peptidyl-lysine modification to peptidyl-hypusine IMP
IMP: Inferred from mutant phenotype
24196968 MGI
involved in peptidyl-lysine modification to peptidyl-hypusine IMP
IMP: Inferred from mutant phenotype
24196968 MGI
acts upstream of or within positive regulation of T cell proliferation IMP
IMP: Inferred from mutant phenotype
24196968 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in cytosol IDA
IDA: Inferred from direct assay
3126083 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

deoxyhypusine synthase

Related Agents

Approval
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0212 Sulfapyridine Inhibitor 99.85% Yes
HY-B0212R Sulfapyridine (Standard) Inhibitor / Unkown
Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-106927 Bay Y5959 Agonist / Phase 2
HY-106808 Cerebrocrast Inhibitor 99.51% Phase 1
Pre-clinical Phase
Bioactive Molecules (21)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-108314A GC7 Sulfate Inhibitor ≥98.0% Unkown
HY-115712 DHPS-IN-1 Inhibitor 99.30% Unkown
HY-135218A AV-153 free base Activator 99.65% Unkown
HY-108314 GC-7 Inhibitor / Unkown
HY-106832 Vatanidipine Antagonist / Unkown
HY-106832A Vatanidipine hydrochloride Antagonist / Unkown
HY-117090 (rac)-AL-37350A Agonist / Unkown
HY-135218 AV-153 Activator / Unkown
HY-147721 Dihydropteroate synthase-IN-1 Inhibitor / Unkown
HY-155804 RIP1 kinase inhibitor 8 Inhibitor / Unkown
HY-161027 DHP-B Inducer / Unkown
HY-B0612AS Lercanidipine-13C,d3 hydrochloride / Unkown
HY-B0612AS1 Lercanidipine-13C,d3-1 hydrochloride Inhibitor / Unkown
HY-RS03737 DHPS Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-106766 DHP-218 Antagonist / Unkown
HY-120411 Sadopine Modulator / Unkown
HY-126171 Hypusine / Unkown
HY-172109 DNA Gyrase-IN-15 Inhibitor / Unkown
HY-B0612DS1 Lercanidipine-d3 hydrochloride Inhibitor 98.14% Unkown
HY-RS18754 Dhps Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25241 Dhps Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dhps NCBI NCBI:1725