2. Gene
  3. Dcaf1 - DDB1 and CUL4 associated factor 1 Gene

Dcaf1 - DDB1 and CUL4 associated factor 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Vprbp; mKIAA0800; B930007L02Rik

Gene ID: 321006 | Gene type: protein coding

About Dcaf1

Summary

Predicted to enable Estrogen receptor binding activity and histone kinase activity (H2A-T120 specific). Involved in B cell differentiation and V(D)J recombination. Predicted to be located in fibrillar center and nucleoplasm. Predicted to be part of COP9 signalosome and Cul4-RING E3 ubiquitin Ligase complex. Predicted to be active in nucleus. Orthologous to human DCAF1 (DDB1 and CUL4 associated factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Dcaf1 Products(3)

mRNA Protein Name
NM_001015507.3 NP_001015507.1 DDB1- and CUL4-associated factor 1 isoform 3
NM_001373930.1 NP_001360859.1 DDB1- and CUL4-associated factor 1 isoform 1
NM_001373931.1 NP_001360860.1 DDB1- and CUL4-associated factor 1 isoform 2
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in B cell differentiation IMP
IMP: Inferred from mutant phenotype
22157821 MGI
involved in V(D)J recombination IMP
IMP: Inferred from mutant phenotype
22157821 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DDB1- and CUL4-associated factor 1

Vpr (HIV-1) binding protein

protein VPRBP

serine/threonine-protein kinase VPRBP

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-169147 MY-11B / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dcaf1 NCBI NCBI:9730