2. Gene
  3. Sp8 - trans-acting transcription factor 8 Gene

Sp8 - trans-acting transcription factor 8 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as mBtd; D930049B17Rik

Gene ID: 320145 | Gene type: protein coding

About Sp8

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within dorsal/ventral pattern formation; embryonic limb morphogenesis; and proximal/distal pattern formation. Predicted to be located in nucleus. Is expressed in several structures, including 1st branchial arch; brain; embryo ectoderm; sensory organ; and tail bud. Orthologous to human SP8 (Sp8 transcription factor). [provided by Alliance of Genome Resources, Apr 2022]

Sp8 Products(3)

mRNA Protein Name
NM_001379379.1 NP_001366308.1 transcription factor Sp8 isoform 1
NM_001379380.1 NP_001366309.1 transcription factor Sp8 isoform 2
NM_177082.4 NP_796056.2 transcription factor Sp8 isoform 2
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within dorsal/ventral pattern formation IMP
IMP: Inferred from mutant phenotype
14597661 MGI
acts upstream of or within embryonic limb morphogenesis IMP
IMP: Inferred from mutant phenotype
14597661 MGI
involved in embryonic limb morphogenesis IMP
IMP: Inferred from mutant phenotype
15358670 MGI
acts upstream of or within proximal/distal pattern formation IMP
IMP: Inferred from mutant phenotype
14597661 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcription factor Sp8

Related Agents

Pre-clinical Phase
Bioactive Molecules (14)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-120994B Sp-8-CPT-cAMPS Activator / Unkown
HY-137640A Sp-8-Br-cAMPS sodium Agonist / Unkown
HY-RS13611 SP8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-137108 Sp-8-pCPT-cGMPS Activator / Unkown
HY-137628 Sp-8-PIP cAMP Agonist / Unkown
HY-137629 Sp-8-pCPT-PET-cGMPS Activator / Unkown
HY-137630 Sp-8-pCPT-2'-O-Me-cAMPS Activator / Unkown
HY-137632 Sp-8-Cl-cAMPS / Unkown
HY-137633 Sp-8-Br-PET-cGMPS Agonist / Unkown
HY-137639 Sp-8-Br-cGMPS Agonist / Unkown
HY-137640 Sp-8-Br-cAMPS Agonist / Unkown
HY-137641 Sp-8-Br-2'-O-Me-cAMPS Activator / Unkown
HY-RS20685 Sp8 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27196 Sp8 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sp8 NCBI NCBI:221833