2. Gene
  3. Fstl4 - follistatin-like 4 Gene

Fstl4 - follistatin-like 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as SPIG1; mKIAA1061; B230374F23Rik

Gene ID: 320027 | Gene type: protein coding

About Fstl4

Summary

Enables brain-derived neurotrophic factor binding activity. Acts upstream of or within negative regulation of brain-derived neurotrophic factor receptor signaling pathway; negative regulation of collateral sprouting; and negative regulation of dendritic spine development. Located in secretory granule. Is expressed in medulla oblongata basal plate mantle layer; neural retina; olfactory cortex mantle layer; pons mantle layer; and telencephalon mantle layer. Orthologous to human FSTL4 (Follistatin like 4). [provided by Alliance of Genome Resources, Apr 2022]

Fstl4 Products(1)

mRNA Protein Name
NM_177059.4 NP_796033.2 follistatin-related protein 4 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables brain-derived neurotrophic factor binding IDA
IDA: Inferred from direct assay
24573299 MGI
Biological Process GO Annotation Evidence Reference Source
NOT acts upstream of or within negative regulation of axon extension IMP
IMP: Inferred from mutant phenotype
24573299 MGI
acts upstream of or within negative regulation of brain-derived neurotrophic factor receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
24573299 MGI
acts upstream of or within negative regulation of collateral sprouting IMP
IMP: Inferred from mutant phenotype
24573299 MGI
acts upstream of or within negative regulation of dendritic spine development IMP
IMP: Inferred from mutant phenotype
24573299 MGI
acts upstream of or within regulation of collateral sprouting IGI
IGI: Inferred from genetic interaction
24573299 MGI
Cellular Component GO Annotation Evidence Reference Source
located in secretory granule IDA
IDA: Inferred from direct assay
24573299 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

follistatin-related protein 4

follistatin-like protein 4

m-D/Bsp120I 1-1

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05130 FSTL4 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS22517 Fstl4 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fstl4 NCBI NCBI:23105