2. Gene
  3. Nrf1 - nuclear respiratory factor 1 Gene

Nrf1 - nuclear respiratory factor 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Nfe2l1_retired

Gene ID: 312195 | Gene type: protein coding

About Nrf1

Summary

This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. Confusion has occurred in bibliographic databases for genes in the "nuclear respiratory factor" and "nuclear factor (erythroid-derived 2)-like" families due to a shared symbol or alias of Nrf1. [provided by RefSeq, Jul 2008]

Nrf1 Products(1)

mRNA Protein Name
NM_001100708.1 NP_001094178.1 nuclear respiratory factor 1
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in animal organ regeneration IEP
IEP: Inferred from expression pattern
9501001 RGD
involved in response to electrical stimulus IDA
IDA: Inferred from direct assay
9575220 RGD
involved in response to estradiol IEP
IEP: Inferred from expression pattern
15994367 RGD
involved in response to folic acid IEP
IEP: Inferred from expression pattern
17709439 RGD
involved in response to hypoxia IEP
IEP: Inferred from expression pattern
18078825 RGD
involved in response to lipopolysaccharide IEP
IEP: Inferred from expression pattern
18062988 RGD
involved in response to nutrient IEP
IEP: Inferred from expression pattern
33310031 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nuclear respiratory factor 1

NRF-1

alpha palindromic-binding protein

alpha-pal

Related Agents

Pre-clinical Phase
Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-129225 WRR139 Inhibitor 99.71% Unkown
HY-149127 Rosolutamide 99.03% Unkown
HY-125535 OSU-53 / Unkown
HY-172199 THX6 / Unkown
HY-RS09567 NRF1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17333 Nrf1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS23788 Nrf1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nrf1 NCBI NCBI:4899