Samhd1 - SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 Gene

Rattus norvegicus

Gene ID: 311580 | Gene type: protein coding

About Samhd1

Summary

Predicted to enable several functions, including dGTP binding activity; dGTPase activity; and nucleic acid binding activity. Predicted to be involved in several processes, including DNA metabolic process; protein homotetramerization; and purine deoxyribonucleoside triphosphate catabolic process. Predicted to be located in nucleoplasm; site of double-strand break; and tetraspanin-enriched microdomain. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Aicardi-Goutieres syndrome; Chilblain lupus; acute myeloid leukemia; hepatitis B; and hepatitis C. Orthologous to human SAMHD1 (SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1). [provided by Alliance of Genome Resources, Apr 2022]

Samhd1 Products(1)

mRNA	Protein	Name
NM_001191743.1	NP_001178672.1	deoxynucleoside triphosphate triphosphohydrolase SAMHD1

Protein Preferred Names

Protein Names

deoxynucleoside triphosphate triphosphohydrolase SAMHD1

SAM domain and HD domain, 1

SAM domain and HD domain-containing protein 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (8)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-B1299A	Cephalosporin C zinc salt	Inhibitor	99.31%	Unkown
HY-161296	TH6342	Inhibitor	99.15%	Unkown
HY-RS12433	SAMHD1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-137613	Sp-TTPαS	Inhibitor	/	Unkown
HY-137613A	Sp-TTPαS tetrasodium	Inhibitor	/	Unkown
HY-137618B	Rp-dGTPαS		/	Unkown
HY-RS17783	Samhd1 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS24250	Samhd1 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Samhd1	NCBI	NCBI:25939

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