2. Gene
  3. Herc2 - HECT and RLD domain containing E3 ubiquitin protein ligase 2 Gene

Herc2 - HECT and RLD domain containing E3 ubiquitin protein ligase 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 308669 | Gene type: protein coding

About Herc2

Summary

Predicted to enable SUMO binding activity; ubiquitin protein Ligase activity; and ubiquitin protein Ligase binding activity. Predicted to be involved in cellular response to DNA damage stimulus; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein ubiquitination. Predicted to act upstream of or within spermatogenesis. Predicted to be located in cytosol; nucleus; and plasma membrane. Predicted to be active in cytoplasm and membrane. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability and pigmentation disease. Orthologous to human HERC2 (HECT and RLD domain containing E3 ubiquitin protein Ligase 2). [provided by Alliance of Genome Resources, Apr 2022]

Herc2 Products(1)

mRNA Protein Name
NM_001107520.1 NP_001100990.1 E3 ubiquitin-protein ligase HERC2
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase HERC2

hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 2

hect domain and RLD 2

probable E3 ubiquitin-protein ligase HERC2

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06127 HERC2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19689 Herc2 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26183 Herc2 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Herc2 NCBI NCBI:8924