HMGB3 - Hmgb3 high mobility group box 3 Gene

Rattus norvegicus

Also known as RGD1564407

Gene ID: 305373 | Gene type: protein coding

About HMGB3

Summary

Predicted to enable DNA binding activity, bending; RNA binding activity; and four-way junction DNA binding activity. Predicted to be involved in DNA geometric change and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within negative regulation of B cell differentiation and negative regulation of myeloid cell differentiation. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in syndromic microphthalmia 13. Orthologous to human HMGB3 (high mobility group box 3). [provided by Alliance of Genome Resources, Apr 2022]

HMGB3 Products(3)

mRNA	Protein	Name
NM_001173341.2	NP_001166812.1	high mobility group protein B3 isoform 1
NM_001398776.1	NP_001385705.1	high mobility group protein B3 isoform 2
NM_001398777.1	NP_001385706.1	high mobility group protein B3 isoform 3

Protein Preferred Names

Protein Names

high mobility group protein B3

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06234	HMGB3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS17980	Hmgb3 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS24451	Hmgb3 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	HMGB3	NCBI	NCBI:3149

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