2. Gene
  3. Pus1 - pseudouridine synthase 1 Gene

Pus1 - pseudouridine synthase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 304567 | Gene type: protein coding

About Pus1

Summary

Predicted to enable several functions, including RNA binding activity; nuclear receptor coactivator activity; and tRNA pseudouridine synthase activity. Predicted to be involved in mRNA pseudouridine synthesis and tRNA pseudouridine synthesis. Predicted to act upstream of or within positive regulation of transcription by RNA polymerase II. Predicted to be located in mitochondrion; nucleolus; and nucleoplasm. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in myopathy, lactic acidosis, and sideroblastic anemia 1. Orthologous to human PUS1 (pseudouridine synthase 1). [provided by Alliance of Genome Resources, Apr 2022]

Pus1 Products(1)

mRNA Protein Name
NM_001025563.1 NP_001020734.1 pseudouridylate synthase 1 homolog
Protein Preferred Names Protein Names

pseudouridylate synthase 1 homolog

tRNA pseudouridine synthase A

pseudouridylate synthase 1

tRNA pseudouridine synthase 1

tRNA pseudouridine synthase A, mitochondrial

tRNA pseudouridine(38-40) synthase

tRNA pseudouridylate synthase I

tRNA-uridine isomerase I

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11467 PUS1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20804 Pus1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27318 Pus1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pus1 NCBI NCBI:80324