2. Gene
  3. Amot - angiomotin Gene

Amot - angiomotin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as RGD1564027

Gene ID: 300289 | Gene type: protein coding

About Amot

Summary

Predicted to enable angiostatin binding activity and signaling receptor activity. Predicted to be involved in several processes, including establishment of cell polarity involved in ameboidal cell migration; hippo signaling; and positive regulation of blood vessel endothelial cell migration. Predicted to act upstream of or within several processes, including gastrulation; negative regulation of GTPase activity; and vasculogenesis. Predicted to be located in several cellular components, including actin cytoskeleton; external side of plasma membrane; and ruffle. Predicted to be integral component of membrane. Predicted to be part of COP9 signalosome. Predicted to be active in several cellular components, including bicellular tight junction; cytoplasmic vesicle; and lamellipodium. Orthologous to human AMOT (angiomotin). [provided by Alliance of Genome Resources, Apr 2022]

Amot Products(6)

mRNA Protein Name
XM_006257423.4 XP_006257485.2 angiomotin isoform X1
XM_006257420.4 XP_006257482.2 angiomotin isoform X1
XM_006257422.2 XP_006257484.2 angiomotin isoform X1
XM_006257421.2 XP_006257483.2 angiomotin isoform X1
XM_006257424.4 XP_006257486.2 angiomotin isoform X2
XM_039100625.1 XP_038956553.1 angiomotin isoform X2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
21481793 RGD
Biological Process GO Annotation Evidence Reference Source
involved in regulation of modification of postsynaptic actin cytoskeleton IDA
IDA: Inferred from direct assay
29317530 RGD
involved in regulation of modification of postsynaptic actin cytoskeleton IMP
IMP: Inferred from mutant phenotype
29317530 RGD
Cellular Component GO Annotation Evidence Reference Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
29317530 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
29317530 RGD
is active in postsynaptic density IDA
IDA: Inferred from direct assay
29317530 RGD
is active in postsynaptic density IMP
IMP: Inferred from mutant phenotype
29317530 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

angiomotin

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00663 AMOT Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20691 Amot Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27202 Amot Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Amot NCBI NCBI:154796