2. Gene
  3. Flrt2 - fibronectin leucine rich transmembrane protein 2 Gene

Flrt2 - fibronectin leucine rich transmembrane protein 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 299236 | Gene type: protein coding

About Flrt2

Summary

Predicted to enable chemorepellent activity and Fibroblast Growth Factor receptor binding activity. Predicted to be involved in basement membrane organization; cell adhesion involved in heart morphogenesis; and Fibroblast Growth Factor receptor signaling pathway. Predicted to act upstream of or within axon guidance; positive regulation of synapse assembly; and regulation of neuron migration. Predicted to be located in cell-cell junction. Predicted to be integral component of plasma membrane. Predicted to be active in extracellular space. Predicted to colocalize with focal adhesion. Orthologous to human FLRT2 (fibronectin leucine rich transmembrane protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Flrt2 Products(1)

mRNA Protein Name
NM_001106750.1 NP_001100220.1 leucine-rich repeat transmembrane protein FLRT2 precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in regulation of postsynapse assembly IDA
IDA: Inferred from direct assay
29983322 RGD
involved in regulation of postsynapse assembly IMP
IMP: Inferred from mutant phenotype
29983322 RGD
Cellular Component GO Annotation Evidence Reference Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
29983322 RGD
is active in postsynaptic membrane IDA
IDA: Inferred from direct assay
29983322 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

leucine-rich repeat transmembrane protein FLRT2

fibronectin-like domain-containing leucine-rich transmembrane protein 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04985 FLRT2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20020 Flrt2 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26523 Flrt2 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Flrt2 NCBI NCBI:23768
Mus musculus Flrt2 NCBI NCBI:399558