Clic2 - chloride intracellular channel 2 Gene

About Clic2

Summary

Predicted to enable Chloride Channel activity and Glutathione Peroxidase activity. Predicted to be involved in chloride transport; positive regulation of binding activity; and regulation of release of sequestered calcium ion into cytosol. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Predicted to be part of Chloride Channel complex. Predicted to be active in cytoplasm and membrane. Human ortholog(s) of this gene implicated in X-linked intellectual disability-cardiomegaly-congestive heart failure syndrome. Orthologous to human CLIC2 (chloride intracellular channel 2). [provided by Alliance of Genome Resources, Apr 2022]