2. Gene
  3. Pfas - phosphoribosylformylglycinamidine synthase Gene

Pfas - phosphoribosylformylglycinamidine synthase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 287420 | Gene type: protein coding

About Pfas

Summary

Predicted to enable phosphoribosylformylglycinamidine synthase activity. Involved in glutamine metabolic process; response to xenobiotic stimulus; and ribonucleoside monophosphate biosynthetic process. Biomarker of hepatocellular carcinoma. Orthologous to human PFAS (phosphoribosylformylglycinamidine synthase). [provided by Alliance of Genome Resources, Apr 2022]

Pfas Products(1)

mRNA Protein Name
NM_001395097.1 NP_001382026.1 phosphoribosylformylglycinamidine synthase
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in glutamine metabolic process IDA
IDA: Inferred from direct assay
3436958 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
6206692 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phosphoribosylformylglycinamidine synthase

FGAM synthetase

phosphoribosylformylglycinamidine synthase (FGAR amidotransferase)

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-115701 1-Stearoyl-2-15(S)-Hpete-Sn-Glycero-3-Pe Inducer / Unkown
HY-RS10357 PFAS Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-169848 (S)-Batylalcohol Inhibitor / Unkown
HY-RS19931 Pfas Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26433 Pfas Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pfas NCBI NCBI:5198