Gpr3 - G protein-coupled receptor 3 Gene

Rattus norvegicus

Also known as Gpcr3

Gene ID: 266769 | Gene type: protein coding

About Gpr3

Summary

Predicted to enable G protein-coupled receptor activity. Involved in positive regulation of cAMP-mediated signaling and regulation of cytosolic calcium ion concentration. Predicted to be located in nuclear membrane. Predicted to be active in cytoplasm and plasma membrane. Orthologous to human GPR3 (G protein-coupled receptor 3). [provided by Alliance of Genome Resources, Apr 2022]

Gpr3 Products(1)

mRNA	Protein	Name
NM_153727.2	NP_714949.2	G-protein coupled receptor 3

Gene Ontology

Biological Process

Biological Process GO Annotation	Evidence	Reference	Source
involved in positive regulation of cAMP/PKA signal transduction	IDA IDA: Inferred from direct assay	12220620	RGD
involved in regulation of cytosolic calcium ion concentration	IDA IDA: Inferred from direct assay	12220620	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

G-protein coupled receptor 3

G protein-coupled receptor R4

Related Agents

Clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-108496	Sphingosine-1-phosphate	Agonist	99.54%	Phase 1

Pre-clinical Phase

Bioactive Molecules (6)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-12664	AF64394	Agonist	98.01%	Unkown
HY-155318A	GPR3 agonist-2	Agonist	99.90%	Unkown
HY-108496S	Sphingosine-1-phosphate-d7	Agonist	99.00%	Unkown
HY-RS05700	GPR3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS17955	Gpr3 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS24426	Gpr3 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Gpr3	NCBI	NCBI:2827

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