2. Gene
  3. Grk6 - G protein-coupled receptor kinase 6 Gene

Grk6 - G protein-coupled receptor kinase 6 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Gprk6

Gene ID: 26385 | Gene type: protein coding

About Grk6

Summary

Enables protein kinase activity. Involved in protein phosphorylation. Predicted to be located in cytosol. Predicted to be active in cytoplasm and plasma membrane. Is expressed in several structures, including genitourinary system; liver; lung; spleen; and submandibular gland primordium. Human ortholog(s) of this gene implicated in Parkinson's disease. Orthologous to human GRK6 (G protein-coupled receptor kinase 6). [provided by Alliance of Genome Resources, Apr 2022]

Grk6 Products(9)

mRNA Protein Name
NM_001038018.5 NP_001033107.1 G protein-coupled receptor kinase 6 isoform a
NM_001112711.2 NP_001106182.1 G protein-coupled receptor kinase 6 isoform c
NM_001286063.2 NP_001272992.1 G protein-coupled receptor kinase 6 isoform d
NM_001286064.2 NP_001272993.1 G protein-coupled receptor kinase 6 isoform e
NM_001286065.1 NP_001272994.1 G protein-coupled receptor kinase 6 isoform f
NM_001286066.2 NP_001272995.1 G protein-coupled receptor kinase 6 isoform g
NM_001377076.1 NP_001364005.1 G protein-coupled receptor kinase 6 isoform h
NM_001377077.1 NP_001364006.1 G protein-coupled receptor kinase 6 isoform i
NM_011938.5 NP_036068.2 G protein-coupled receptor kinase 6 isoform b
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
10446210 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

G protein-coupled receptor kinase 6

g protein-coupled receptor kinase GRK6

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-128231 GRK6-IN-4 Inhibitor / Phase 1
Pre-clinical Phase
Bioactive Molecules (9)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-142812 GRK6-IN-1 99.61% Unkown
HY-142817 GRK6-IN-2 98.98% Unkown
HY-128311 GRK6-IN-3 Inhibitor / Unkown
HY-150021 GRK5-IN-3 Inhibitor / Unkown
HY-RS05817 GRK6 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-159996 GRL093-22 Inhibitor / Unkown
HY-169678 GRK6-IN-5 Inhibitor / Unkown
HY-RS17369 Grk6 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS23823 Grk6 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Grk6 NCBI NCBI:2870