Cenpf - centromere protein F Gene

Also known as Lek1

About Cenpf

Summary

Predicted to enable several functions, including dynein complex binding activity; protein C-terminus binding activity; and protein homodimerization activity. Predicted to be involved in several processes, including metaphase plate congression; regulation of G2/M transition of mitotic cell cycle; and ventricular system development. Predicted to act upstream of or within regulation of striated muscle tissue development. Predicted to be located in several cellular components, including cytoskeleton; midbody; and nucleus. Predicted to be part of ciliary transition fiber and outer kinetochore. Predicted to be active in chromosome, centromeric region; nucleus; and spindle pole. Human ortholog(s) of this gene implicated in Stromme syndrome. Orthologous to human CENPF (centromere protein F). [provided by Alliance of Genome Resources, Apr 2022]