2. Gene
  3. Gpd2 - glycerol-3-phosphate dehydrogenase 2 Gene

Gpd2 - glycerol-3-phosphate dehydrogenase 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as mtGPDH

Gene ID: 25062 | Gene type: protein coding

About Gpd2

Summary

Enables glycerol-3-phosphate dehydrogenase [NAD+] activity. Involved in NADH metabolic process and glycerol-3-phosphate metabolic process. Predicted to be part of glycerol-3-phosphate dehydrogenase complex. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human GPD2 (glycerol-3-phosphate dehydrogenase 2). [provided by Alliance of Genome Resources, Apr 2022]

Gpd2 Products(1)

mRNA Protein Name
NM_012736.2 NP_036868.1 glycerol-3-phosphate dehydrogenase, mitochondrial precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in NADH metabolic process IDA
IDA: Inferred from direct assay
12351438 RGD
involved in glycerol-3-phosphate metabolic process IDA
IDA: Inferred from direct assay
12351438 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glycerol-3-phosphate dehydrogenase, mitochondrial

GPD-M

GPDH-M

Glycerol-3-phosophate dehydrogenase 2 (mitochondrial)

glycerol-3-phosphate dehydrogenase 2, mitochondrial

mtGPDH gene, promoter region and alternative transcripts

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-148685 KM04416 Inhibitor 98.76% Unkown
HY-RS05635 GPD2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17954 Gpd2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24425 Gpd2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gpd2 NCBI NCBI:2820