2. Gene
  3. Tmbim6 - transmembrane BAX inhibitor motif containing 6 Gene

Tmbim6 - transmembrane BAX inhibitor motif containing 6 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Tegt; Cc1-27; Ab1-011; Ac1-149

Gene ID: 24822 | Gene type: protein coding

About Tmbim6

Summary

Predicted to enable endoribonuclease inhibitor activity and ubiquitin protein Ligase binding activity. Involved in lung development and spermatogenesis. Predicted to be located in endoplasmic reticulum membrane and mitochondrial membrane. Biomarker of invasive ductal carcinoma. Orthologous to human TMBIM6 (transmembrane Bax Inhibitor motif containing 6). [provided by Alliance of Genome Resources, Apr 2022]

Tmbim6 Products(1)

mRNA Protein Name
NM_019381.2 NP_062254.2 bax inhibitor 1
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in lung development IEP
IEP: Inferred from expression pattern
10198159 RGD
involved in spermatogenesis IEP
IEP: Inferred from expression pattern
8012111 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

bax inhibitor 1

BI-1

Bax inhibitor-1

testis enhanced gene transcript

testis-enhanced gene transcript protein

transmembrane BAX inhibitor motif-containing protein 6

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-137175 TMBIM6 antagonist-1 Antagonist 99.60% Unkown
HY-161388 NSCLC-IN-1 Inducer / Unkown
HY-RS14620 TMBIM6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19822 Tmbim6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26318 Tmbim6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tmbim6 NCBI NCBI:7009