2. Gene
  3. Ppm1a - protein phosphatase, Mg2+/Mn2+ dependent, 1A Gene

Ppm1a - protein phosphatase, Mg2+/Mn2+ dependent, 1A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Pp2c1

Gene ID: 24666 | Gene type: protein coding

About Ppm1a

Summary

Enables protein C-terminus binding activity and transmembrane transporter binding activity. Predicted to be involved in cellular protein modification process; positive regulation of transcription, DNA-templated; and regulation of signal transduction. Predicted to act upstream of or within cellular response to transforming growth factor beta stimulus; negative regulation of BMP signaling pathway; and positive regulation of protein export from nucleus. Located in neuron projection. Orthologous to human PPM1A (protein Phosphatase, Mg2+/Mn2+ dependent 1A). [provided by Alliance of Genome Resources, Apr 2022]

Ppm1a Products(1)

mRNA Protein Name
NM_017038.2 NP_058734.1 protein phosphatase 1A
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables phosphoprotein phosphatase activity IDA
IDA: Inferred from direct assay
16844074 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
15728831 RGD
enables transmembrane transporter binding IDA
IDA: Inferred from direct assay
15728831 RGD
Cellular Component GO Annotation Evidence Reference Source
located in neuron projection IDA
IDA: Inferred from direct assay
15728831 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein phosphatase 1A

IA

PP2C-alpha

protein phosphatase IA

Related Agents

Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-164220 PPM1A-IN-1 Inhibitor ≥95.0% Unkown
HY-163782 SMIP-031 / Unkown
HY-P10359 TAT-QFNP12 Inhibitor / Unkown
HY-RS10960 PPM1A Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17113 Ppm1a Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS23558 Ppm1a Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ppm1a NCBI NCBI:5494
Mus musculus Ppm1a NCBI NCBI:19042