2. Gene
  3. Lgi4 - leucine-rich repeat LGI family, member 4 Gene

Lgi4 - leucine-rich repeat LGI family, member 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as clp; Lgil3

Gene ID: 243914 | Gene type: protein coding

About Lgi4

Summary

Involved in regulation of myelination. Acts upstream of or within adult locomotory behavior and neurogenesis. Located in extracellular space. Is expressed in several structures, including adipose tissue; alimentary system; nervous system; reproductive system; and sensory organ. Human ortholog(s) of this gene implicated in arthrogryposis multiplex congenita-1 and childhood absence epilepsy. Orthologous to human LGI4 (leucine rich repeat LGI family member 4). [provided by Alliance of Genome Resources, Apr 2022]

Lgi4 Products(1)

mRNA Protein Name
NM_144556.2 NP_653139.2 leucine-rich repeat LGI family member 4 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
20220021 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within Schwann cell development IMP
IMP: Inferred from mutant phenotype
21068328 MGI
acts upstream of or within adult locomotory behavior IMP
IMP: Inferred from mutant phenotype
1652607 MGI
acts upstream of or within glial cell development IMP
IMP: Inferred from mutant phenotype
21068328 MGI
acts upstream of or within glial cell proliferation IDA
IDA: Inferred from direct assay
21068328 MGI
acts upstream of or within gliogenesis IGI
IGI: Inferred from genetic interaction
21068328 MGI
acts upstream of or within gliogenesis IMP
IMP: Inferred from mutant phenotype
21068328 MGI
acts upstream of or within myelination IDA
IDA: Inferred from direct assay
16341215 MGI
acts upstream of or within myelination IMP
IMP: Inferred from mutant phenotype
15282162 MGI
acts upstream of or within myelination in peripheral nervous system IMP
IMP: Inferred from mutant phenotype
1652607 MGI
acts upstream of or within neuron maturation IMP
IMP: Inferred from mutant phenotype
15282162 MGI
involved in regulation of myelination IDA
IDA: Inferred from direct assay
16341215 MGI
Cellular Component GO Annotation Evidence Reference Source
located in extracellular space IDA
IDA: Inferred from direct assay
16341215 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

leucine-rich repeat LGI family member 4

LGI1-like protein 3

leucine-rich glioma inactivated protein 4

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07616 LGI4 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS16306 Lgi4 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lgi4 NCBI NCBI:163175