2. Gene
  3. Hax1 - HCLS1 associated X-1 Gene

Hax1 - HCLS1 associated X-1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as HAX-1; Hs1bp1; SIG-111; Silg111; mHAX-1s; HSP1BP-1

Gene ID: 23897 | Gene type: protein coding

About Hax1

Summary

Predicted to enable interleukin-1 binding activity; protein N-terminus binding activity; and protein domain specific binding activity. Predicted to be involved in several processes, including positive regulation of intracellular signal transduction; positive regulation of protein phosphorylation; and regulation of actin Cytoskeleton organization. Predicted to act upstream of or within cell surface receptor signaling pathway. Located in several cellular components, including actin cytoskeleton; lamellipodium; and sarcoplasmic reticulum. Is expressed in coelomic epithelium of testis; ovary; and testis mesenchyme. Human ortholog(s) of this gene implicated in severe congenital neutropenia 3. Orthologous to human HAX1 (HCLS1 associated protein X-1). [provided by Alliance of Genome Resources, Apr 2022]

Hax1 Products(3)

mRNA Protein Name
NM_001282032.1 NP_001268961.1 HCLS1-associated protein X-1 isoform 2
NM_001310681.1 NP_001297610.1 HCLS1-associated protein X-1 isoform 3
NM_011826.4 NP_035956.1 HCLS1-associated protein X-1 isoform 1
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
10760273 MGI
Cellular Component GO Annotation Evidence Reference Source
located in actin cytoskeleton IDA
IDA: Inferred from direct assay
10760273 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
10760273 MGI
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
10760273 MGI
located in lamellipodium IDA
IDA: Inferred from direct assay
10760273 MGI
located in mitochondrial matrix IDA
IDA: Inferred from direct assay
26915802 MGI
located in mitochondrion IDA
IDA: Inferred from direct assay
9058808 MGI
located in sarcoplasmic reticulum IDA
IDA: Inferred from direct assay
19920172 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

HCLS1-associated protein X-1

HS1 binding protein

HS1-associated protein X-1

HS1-associating protein X-1

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06023 HAX1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22196 Hax1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hax1 NCBI NCBI:10456