2. Gene
  3. Rin1 - Ras and Rab interactor 1 Gene

Rin1 - Ras and Rab interactor 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus
Gene ID: 225870 | Gene type: protein coding

About Rin1

Summary

Enables small GTPase binding activity. Acts upstream of or within associative learning; memory; and negative regulation of synaptic plasticity. Located in dendrite and neuronal cell body. Is expressed in brain; gonad; and thyroid gland. Orthologous to human RIN1 (Ras and Rab interactor 1). [provided by Alliance of Genome Resources, Apr 2022]

Rin1 Products(3)

mRNA Protein Name
NM_001374051.1 NP_001360980.1 ras and Rab interactor 1 isoform 1
NM_001374052.1 NP_001360981.1 ras and Rab interactor 1 isoform 3
NM_145495.3 NP_663470.1 ras and Rab interactor 1 isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
18723684 MGI
enables small GTPase binding IDA
IDA: Inferred from direct assay
12574403 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within associative learning IMP
IMP: Inferred from mutant phenotype
12574403 MGI
acts upstream of or within memory IMP
IMP: Inferred from mutant phenotype
12574403 MGI
acts upstream of or within negative regulation of synaptic plasticity IMP
IMP: Inferred from mutant phenotype
12574403 MGI
Cellular Component GO Annotation Evidence Reference Source
located in dendrite IDA
IDA: Inferred from direct assay
12574403 MGI
located in neuronal cell body IDA
IDA: Inferred from direct assay
12574403 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ras and Rab interactor 1

ras interaction/interference protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (12)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-137471 RBPJ Inhibitor-1 Inhibitor 99.80% Unkown
HY-101774 CSF1R-IN-1 Inhibitor 98.04% Unkown
HY-100328 CB2R-IN-1 Inhibitor / Unkown
HY-149014 OX2R-IN-1 Inhibitor / Unkown
HY-149358 NK3R-IN-1 Inhibitor / Unkown
HY-159941 tau-0N4R-IN-1 Inhibitor / Unkown
HY-162062 EGFR WT/T790M/L858R-IN-1 Inhibitor / Unkown
HY-170687 AT2R-IN-1 Inhibitor / Unkown
HY-176405 σ1R-IN-1 Inhibitor / Unkown
HY-RS11982 RIN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17055 Rin1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23499 Rin1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rin1 NCBI NCBI:9610
Macaca fascicularis Rin1 NCBI NCBI:102132424