2. Gene
  3. Aldh4a1 - aldehyde dehydrogenase 4 family, member A1 Gene

Aldh4a1 - aldehyde dehydrogenase 4 family, member A1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Ahd1; P5cd; Ahd-1; Aldh4; P5cdh; Ssdh1; P5cdhl; P5cdhs; Aldh5a1; E330022C09; A930035F14Rik

Gene ID: 212647 | Gene type: protein coding

About Aldh4a1

Summary

Enables 1-pyrroline-5-carboxylate dehydrogenase activity. Predicted to be involved in proline catabolic process to glutamate. Predicted to act upstream of or within proline metabolic process. Located in mitochondrion. Is expressed in several structures, including alimentary system; brain; integumental system; metanephros; and respiratory system. Human ortholog(s) of this gene implicated in hyperprolinemia type 2. Orthologous to human ALDH4A1 (aldehyde dehydrogenase 4 family member A1). [provided by Alliance of Genome Resources, Apr 2022]

Aldh4a1 Products(1)

mRNA Protein Name
NM_175438.4 NP_780647.3 delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables 1-pyrroline-5-carboxylate dehydrogenase activity IDA
IDA: Inferred from direct assay
23928095 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial

L-glutamate gamma-semialdehyde dehydrogenase

P5C dehydrogenase

aldehyde dehydrogenase family 4 member A1

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00577 ALDH4A1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20621 Aldh4a1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27129 Aldh4a1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Aldh4a1 NCBI NCBI:8659