2. Gene
  3. Srsf5 - serine and arginine-rich splicing factor 5 Gene

Srsf5 - serine and arginine-rich splicing factor 5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Sfrs5

Gene ID: 20384 | Gene type: protein coding

About Srsf5

Summary

The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding Other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. [provided by RefSeq, Nov 2016]

Srsf5 Products(10)

mRNA Protein Name
NM_001079694.3 NP_001073162.1 serine/arginine-rich splicing factor 5 isoform 1
NM_001079695.3 NP_001073163.1 serine/arginine-rich splicing factor 5 isoform 1
NM_001347415.2 NP_001334344.1 serine/arginine-rich splicing factor 5 isoform 2
NM_001347416.2 NP_001334345.1 serine/arginine-rich splicing factor 5 isoform 2
NM_001409833.1 NP_001396762.1 serine/arginine-rich splicing factor 5 isoform 3
NM_001409834.1 NP_001396763.1 serine/arginine-rich splicing factor 5 isoform 4
NM_001409835.1 NP_001396764.1 serine/arginine-rich splicing factor 5 isoform 5
NM_001409836.1 NP_001396765.1 serine/arginine-rich splicing factor 5 isoform 5
NM_001409837.1 NP_001396766.1 serine/arginine-rich splicing factor 5 isoform 2
NM_009159.4 NP_033185.2 serine/arginine-rich splicing factor 5 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables RS domain binding IPI
IPI: Inferred from physical interaction
15798186 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
18758164 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within response to wounding IDA
IDA: Inferred from direct assay
9857059 MGI
Cellular Component GO Annotation Evidence Reference Source
located in nuclear speck IDA
IDA: Inferred from direct assay
18758164 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine/arginine-rich splicing factor 5

delayed-early protein HRS

pre-mRNA-splicing factor SRP40

splicing factor, arginine/serine-rich 5 (SRp40, HRS)

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13796 SRSF5 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS22832 Srsf5 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Srsf5 NCBI NCBI:6430