2. Gene
  3. Sel1l - sel-1 suppressor of lin-12-like (C. elegans) Gene

Sel1l - sel-1 suppressor of lin-12-like (C. elegans) Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Sel1h; mKIAA4137

Gene ID: 20338 | Gene type: protein coding

About Sel1l

Summary

Predicted to contribute to ubiquitin-protein transferase activity. Involved in ERAD pathway; protein secretion; and triglyceride metabolic process. Acts upstream of or within response to endoplasmic reticulum stress. Predicted to be located in endoplasmic reticulum. Predicted to be part of Derlin-1 retrotranslocation complex and Hrd1p ubiquitin Ligase ERAD-L complex. Is expressed in several structures, including genitourinary system; liver; neural tube; pancreas; and spleen. Human ortholog(s) of this gene implicated in pancreatic Cancer. Orthologous to human SEL1L (SEL1L adaptor subunit of ERAD E3 ubiquitin Ligase). [provided by Alliance of Genome Resources, Apr 2022]

Sel1l Products(2)

mRNA Protein Name
NM_001039089.1 NP_001034178.1 protein sel-1 homolog 1 isoform a precursor
NM_011344.2 NP_035474.1 protein sel-1 homolog 1 isoform b precursor
Protein Preferred Names Protein Names

protein sel-1 homolog 1

Sel1 (suppressor of lin-12) 1 homolog

sel-1L

suppressor of lin-12-like protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12630 SEL1L Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS12631 SEL1L3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS22799 Sel1l Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sel1l NCBI NCBI:6400