2. Gene
  3. Map1b - microtubule-associated protein 1B Gene

Map1b - microtubule-associated protein 1B Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as LC1; MAP5; Mtap5; Mtap-5; Mtap1b; A230055D22

Gene ID: 17755 | Gene type: protein coding

About Map1b

Summary

Predicted to enable actin binding activity; microtubule binding activity; and phospholipid binding activity. Acts upstream of or within several processes, including establishment of monopolar cell polarity; mitochondrion transport along microtubule; and neuron projection development. Located in several cellular components, including neuronal cell body; photoreceptor outer segment; and postsynaptic density. Is expressed in several structures, including central nervous system; genitourinary system; intestine smooth muscle circular layer; nose; and trigeminal nerve. Human ortholog(s) of this gene implicated in periventricular nodular heterotopia. Orthologous to human MAP1B (microtubule associated protein 1B). [provided by Alliance of Genome Resources, Apr 2022]

Map1b Products(1)

mRNA Protein Name
NM_008634.2 NP_032660.2 microtubule-associated protein 1B
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
17308336 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within axon extension IMP
IMP: Inferred from mutant phenotype
16536727 MGI
acts upstream of or within axonogenesis IGI
IGI: Inferred from genetic interaction
11891784 MGI
acts upstream of or within dendrite development IMP
IMP: Inferred from mutant phenotype
11581286 MGI
acts upstream of or within establishment of monopolar cell polarity IMP
IMP: Inferred from mutant phenotype
11029282 MGI
acts upstream of intracellular transport IMP
IMP: Inferred from mutant phenotype
16536727 MGI
acts upstream of or within microtubule bundle formation IMP
IMP: Inferred from mutant phenotype
11581286 MGI
acts upstream of or within mitochondrion transport along microtubule IMP
IMP: Inferred from mutant phenotype
16536727 MGI
acts upstream of or within negative regulation of intracellular transport IMP
IMP: Inferred from mutant phenotype
16536727 MGI
involved in regulation of postsynapse assembly IDA
IDA: Inferred from direct assay
21984824 MGI
involved in regulation of postsynapse assembly IMP
IMP: Inferred from mutant phenotype
21984824 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytosol IDA
IDA: Inferred from direct assay
16885219 MGI
located in dendrite IDA
IDA: Inferred from direct assay
25788676 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
21984824 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
21984824 MGI
located in neuronal cell body IDA
IDA: Inferred from direct assay
25788676 MGI
located in photoreceptor outer segment IDA
IDA: Inferred from direct assay
24664738 MGI
is active in postsynapse IDA
IDA: Inferred from direct assay
21984824 MGI
located in postsynaptic density IDA
IDA: Inferred from direct assay
17114649 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

microtubule-associated protein 1B

MAP-1B

MAP1(X)

MAP1.2

Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X))

microtubule-associated protein 5

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08027 MAP1B Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18395 Map1b Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24876 Map1b Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Map1b NCBI NCBI:4131