2. Gene
  3. mt-Nd5 - NADH dehydrogenase 5, mitochondrial Gene

mt-Nd5 - NADH dehydrogenase 5, mitochondrial Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus (strain: C57BL/6J)

Also known as ND5

Gene ID: 17721 | Gene type: protein coding

About mt-Nd5

Summary

Contributes to NADH dehydrogenase (ubiquinone) activity. Predicted to be involved in electron transport coupled proton transport; mitochondrial electron transport, NADH to ubiquinone; and mitochondrial respiratory chain complex I assembly. Located in mitochondrion. Is expressed in central nervous system; heart; liver; metanephros; and retina. Human ortholog(s) of this gene implicated in Leber hereditary optic neuropathy; Leigh disease; and MELAS syndrome. Orthologous to human MT-ND5 (mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5). [provided by Alliance of Genome Resources, Apr 2022]

mt-Nd5 Products(2)

mRNA Protein Name
NP_904338.1 NADH dehydrogenase subunit 5 (mitochondrion) [Mus musculus]
NP_904338.1 NADH dehydrogenase subunit 5 (mitochondrion) [Mus musculus]
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
contributes to NADH dehydrogenase (ubiquinone) activity IDA
IDA: Inferred from direct assay
18729827 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

NADH dehydrogenase subunit 5

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS21159 mt-Nd5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08801 MT-ND5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27675 mt-Nd5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens mt-Nd5 NCBI NCBI:4540