2. Gene
  3. Mak - male germ cell-associated kinase Gene

Mak - male germ cell-associated kinase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as A930010O05Rik

Gene ID: 17152 | Gene type: protein coding

About Mak

Summary

Enables protein kinase activity. Acts upstream of or within negative regulation of non-motile cilium assembly and photoreceptor cell maintenance. Located in several cellular components, including axoneme; ciliary tip; and photoreceptor cell cilium. Is expressed in several structures, including brain; nasal cavity epithelium; neural retina; respiratory system; and testis. Human ortholog(s) of this gene implicated in retinitis pigmentosa 62. Orthologous to human MAK (male germ cell associated kinase). [provided by Alliance of Genome Resources, Apr 2022]

Mak Products(3)

mRNA Protein Name
NM_001145802.1 NP_001139274.1 serine/threonine-protein kinase MAK isoform 3
NM_001145803.1 NP_001139275.1 serine/threonine-protein kinase MAK isoform 1
NM_008547.2 NP_032573.2 serine/threonine-protein kinase MAK isoform 2
Protein Preferred Names Protein Names

serine/threonine-protein kinase MAK

protein kinase RCK

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-103663 MAK683 Inhibitor 99.18% Phase 2
Pre-clinical Phase
Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-130815A MAK683-CH2CH2COOH hydrochloride Inhibitor 98.03% Unkown
HY-130815 MAK683-CH2CH2COOH Inhibitor / Unkown
HY-103663A MAK683 hydrochloride Inhibitor / Unkown
HY-RS07989 MAK Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS07990 MAK16 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17873 Mak Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24342 Mak Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P99425 Afelimomab 99.34% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mak NCBI NCBI:4117