Ltc4s - leukotriene C4 synthase Gene

Mus musculus

Gene ID: 17001 | Gene type: protein coding

About Ltc4s

Summary

The protein encoded by this gene is an enzyme that catalyzes the synthesis of leukotriene C4 by combining leukotriene A4 with reduced glutathione. The encoded protein is found in the outer nuclear membrane and in the peripheral endoplasmic reticulum. Leukotrienes have been implicated as mediators of anaphylaxis and inflammatory conditions such as bronchial asthma in humans. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]

Ltc4s Products(2)

mRNA	Protein	Name
NM_001313968.1	NP_001300897.1	leukotriene C4 synthase isoform 2
NM_008521.2	NP_032547.1	leukotriene C4 synthase isoform 1

Protein Preferred Names

Protein Names

leukotriene C4 synthase

LTC4 synthase	glutathione S-transferase LTC4
leukotriene-C(4) synthase

Related Agents

Clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-126329	AZD9898	Inhibitor	98.62%	Phase 1

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-117143	TK05	Inhibitor	97.05%	Unkown
HY-168498	GJG057	Inhibitor	/	Unkown
HY-RS07882	LTC4S Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS21637	Ltc4s Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ltc4s	NCBI	NCBI:4056

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