2. Gene
  3. Ldhb - lactate dehydrogenase B Gene

Ldhb - lactate dehydrogenase B Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Ldh2; H-Ldh; LDH-B; LDH-H; Ldh-2

Gene ID: 16832 | Gene type: protein coding

About Ldhb

Summary

This gene encodes the B subunit of Lactate Dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have also been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Pseudogenes have been identified on chromosomes 1 and 19. [provided by RefSeq, Feb 2016]

Ldhb Products(3)

mRNA Protein Name
NM_001302765.1 NP_001289694.1 L-lactate dehydrogenase B chain isoform 2
NM_001316322.1 NP_001303251.1 L-lactate dehydrogenase B chain isoform Ldhbx
NM_008492.3 NP_032518.1 L-lactate dehydrogenase B chain isoform Ldhb
Protein Preferred Names Protein Names

L-lactate dehydrogenase B chain

LDH heart subunit

lactate dehydrogenase 2, B chain

Related Agents

Pre-clinical Phase
Bioactive Molecules (11)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-W040118 Galloflavin Inhibitor 99.36% Unkown
HY-100742A (R)-GNE-140 Inhibitor 99.73% Unkown
HY-147216 AXKO-0046 Inhibitor 99.77% Unkown
HY-111108 LDH-IN-1 Inhibitor 99.84% Unkown
HY-124309 NHI-2 99.30% Unkown
HY-147216A AXKO-0046 dihydrochloride Inhibitor 99.68% Unkown
HY-152261 MS6105 99.2% Unkown
HY-RS07572 LDHB Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-162629 LDHA-IN-7 Inhibitor / Unkown
HY-RS16989 Ldhb Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS23432 Ldhb Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ldhb NCBI NCBI:3945