2. Gene
  3. Aff3 - AF4/FMR2 family, member 3 Gene

Aff3 - AF4/FMR2 family, member 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Laf4; LAF-4; A730046J16; 3222402O04Rik

Gene ID: 16764 | Gene type: protein coding

About Aff3

Summary

Enables DNA-binding transcription factor activity and double-stranded DNA binding activity. Involved in regulation of transcription, DNA-templated. Acts upstream of or within embryonic hindlimb morphogenesis. Located in nucleus. Is expressed in several structures, including alimentary system; genitourinary system; limb bud; nervous system; and sensory organ. Orthologous to human AFF3 (AF4/FMR2 family member 3). [provided by Alliance of Genome Resources, Apr 2022]

Aff3 Products(1)

mRNA Protein Name
NM_001290814.2 NP_001277743.1 AF4/FMR2 family member 3
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
25162227 MGI
enables DNA-binding transcription factor activity IMP
IMP: Inferred from mutant phenotype
25162227 MGI
enables double-stranded DNA binding IDA
IDA: Inferred from direct assay
25162227 MGI
Biological Process GO Annotation Evidence Reference Source
involved in embryonic hindlimb morphogenesis IEP
IEP: Inferred from expression pattern
18616733 MGI
involved in regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
25162227 MGI
involved in regulation of DNA-templated transcription IMP
IMP: Inferred from mutant phenotype
25162227 MGI
Cellular Component GO Annotation Evidence Reference Source
located in nucleus IDA
IDA: Inferred from direct assay
8555498 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

AF4/FMR2 family member 3

lymphoid nuclear protein 4

lymphoid nuclear protein related to AF4

protein LAF-4

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00430 AFF3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22096 Aff3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28616 Aff3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Aff3 NCBI NCBI:3899