2. Gene
  3. Gsr - glutathione reductase Gene

Gsr - glutathione reductase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Gr1; Gr-1; D8Ertd238e

Gene ID: 14782 | Gene type: protein coding

About Gsr

Summary

Enables glutathione-disulfide reductase (NADPH) activity. Predicted to be involved in several processes, including cell redox homeostasis; cellular response to oxidative stress; and glutathione metabolic process. Located in external side of plasma membrane. Is expressed in brain ventricular layer; gut; lung; metanephros; and retina. Human ortholog(s) of this gene implicated in cataract and macular degeneration. Orthologous to human GSR (glutathione-disulfide reductase). [provided by Alliance of Genome Resources, Apr 2022]

Gsr Products(1)

mRNA Protein Name
NM_010344.4 NP_034474.4 glutathione reductase, mitochondrial precursor
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables glutathione-disulfide reductase (NADPH) activity IDA
IDA: Inferred from direct assay
204065 MGI
Cellular Component GO Annotation Evidence Reference Source
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
24029230 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glutathione reductase, mitochondrial

GR

GRase

glutathione reductase 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-147328 LCS3 Inducer 99.43% Unkown
HY-RS05870 GSR Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18327 Gsr Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24806 Gsr Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gsr NCBI NCBI:2936