2. Gene
  3. Ei24 - etoposide induced 2.4 mRNA Gene

Ei24 - etoposide induced 2.4 mRNA Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as PIG8

Gene ID: 13663 | Gene type: protein coding

About Ei24

Summary

Predicted to enable importin-alpha family protein binding activity. Acts upstream of or within several processes, including cellular response to UV-C; intrinsic apoptotic signaling pathway in response to DNA damage; and negative regulation of protein import into nucleus. Predicted to be located in Golgi apparatus and cytosol. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human EI24 (EI24 Autophagy associated transmembrane protein). [provided by Alliance of Genome Resources, Apr 2022]

Ei24 Products(2)

mRNA Protein Name
NM_001199494.2 NP_001186423.2 etoposide-induced protein 2.4
NM_007915.6 NP_031941.2 etoposide-induced protein 2.4
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within autophagy IMP
IMP: Inferred from mutant phenotype
23074225 MGI
acts upstream of or within cellular response to UV-C IGI
IGI: Inferred from genetic interaction
24014029 MGI
acts upstream of or within intrinsic apoptotic signaling pathway in response to DNA damage IDA
IDA: Inferred from direct assay
10594026 MGI
acts upstream of or within negative regulation of protein import into nucleus IDA
IDA: Inferred from direct assay
24821838 MGI
acts upstream of or within neuromuscular process controlling balance IMP
IMP: Inferred from mutant phenotype
23074225 MGI
acts upstream of or within positive regulation of intrinsic apoptotic signaling pathway IMP
IMP: Inferred from mutant phenotype
17981155 MGI
acts upstream of or within response to xenobiotic stimulus IMP
IMP: Inferred from mutant phenotype
17981155 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

etoposide-induced protein 2.4

p53-induced gene 8 protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04233 EI24 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS22154 Ei24 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ei24 NCBI NCBI:9538