2. Gene
  3. Dao - D-amino acid oxidase Gene

Dao - D-amino acid oxidase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as DAAO; Dao1; DAMOX; Dao-1

Gene ID: 13142 | Gene type: protein coding

About Dao

Summary

Enables D-amino-acid oxidase activity and FAD binding activity. Involved in D-alanine catabolic process. Acts upstream of or within leucine metabolic process. Predicted to be located in cytosol and peroxisomal membrane. Predicted to be active in cytoplasm. Predicted to colocalize with mitochondrial outer membrane. Is expressed in metanephros; renal cortex; ureter; and urinary system. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human DAO (D-amino acid oxidase). [provided by Alliance of Genome Resources, Apr 2022]

Dao Products(3)

mRNA Protein Name
NM_001286396.1 NP_001273325.1 D-amino-acid oxidase isoform 1
NM_001286397.1 NP_001273326.1 D-amino-acid oxidase isoform 2
NM_010018.3 NP_034148.2 D-amino-acid oxidase isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables D-amino-acid dehydrogenase activity IMP
IMP: Inferred from mutant phenotype
1686595 MGI
enables D-amino-acid oxidase activity IDA
IDA: Inferred from direct assay
20567862 MGI
enables FAD binding IDA
IDA: Inferred from direct assay
20603179 MGI
Biological Process GO Annotation Evidence Reference Source
involved in D-alanine catabolic process IDA
IDA: Inferred from direct assay
20603179 MGI
acts upstream of or within L-leucine metabolic process IMP
IMP: Inferred from mutant phenotype
15026304 MGI
involved in digestion IMP
IMP: Inferred from mutant phenotype
6147398 MGI
involved in dopamine biosynthetic process IMP
IMP: Inferred from mutant phenotype
17042912 MGI
involved in killing by host of symbiont cells IDA
IDA: Inferred from direct assay
27670111 MGI
involved in neutrophil-mediated killing of gram-negative bacterium IDA
IDA: Inferred from direct assay
25425233 MGI
Cellular Component GO Annotation Evidence Reference Source
located in extracellular space IDA
IDA: Inferred from direct assay
27670111 MGI
located in peroxisomal matrix IDA
IDA: Inferred from direct assay
1686595 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

D-amino-acid oxidase

D-amino acid oxidase 1

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-P2758 Diamine oxidase / Phase 4
Pre-clinical Phase
Bioactive Molecules (8)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-117292 DAO-IN-2 99.83% Unkown
HY-W037417 DAO-IN-1 Inhibitor 97.46% Unkown
HY-15913 DAOS 99.88% Unkown
HY-RS03523 DAO Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-W027382 SEP-227900 99.40% Unkown
HY-173255 DAO-dBET1 Degrader / Unkown
HY-RS18733 Dao Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25220 Dao Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dao NCBI NCBI:1610