2. Gene
  3. Cdc45 - cell division cycle 45 Gene

Cdc45 - cell division cycle 45 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Cdc45l

Gene ID: 12544 | Gene type: protein coding

About Cdc45

Summary

Predicted to enable DNA replication origin binding activity; chromatin binding activity; and single-stranded DNA binding activity. Predicted to be involved in DNA replication initiation; double-strand break repair via break-induced replication; and mitotic DNA replication preinitiation complex assembly. Predicted to act upstream of or within DNA replication. Predicted to be located in centrosome; ciliary basal body; and nucleoplasm. Predicted to be part of DNA replication preinitiation complex. Is expressed in several structures, including alimentary system; branchial arch; cardiovascular system; central nervous system; and notochord. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 7. Orthologous to human CDC45 (cell division cycle 45). [provided by Alliance of Genome Resources, Apr 2022]

Cdc45 Products(3)

mRNA Protein Name
NM_001161623.2 NP_001155095.1 cell division control protein 45 homolog isoform 2
NM_001358206.1 NP_001345135.1 cell division control protein 45 homolog isoform 3
NM_009862.2 NP_033992.2 cell division control protein 45 homolog isoform 1
Protein Preferred Names Protein Names

cell division control protein 45 homolog

CDC45-related protein

PORC-PI-1

cell division cycle 45 homolog

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02306 CDC45 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20873 Cdc45 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27390 Cdc45 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cdc45 NCBI NCBI:8318