2. Gene
  3. Casp14 - caspase 14 Gene

Casp14 - caspase 14 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as MICE; mini-ICE

Gene ID: 12365 | Gene type: protein coding

About Casp14

Summary

Predicted to enable cysteine-type endopeptidase activity involved in execution phase of Apoptosis. Predicted to be involved in cornification. Predicted to act upstream of or within cell differentiation and proteolysis. Predicted to be located in several cellular components, including keratin filament; mitochondrion; and nucleoplasm. Predicted to be active in cytoplasm. Is expressed in embryo; epidermis; epidermis stratum corneum; and skin. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis. Orthologous to human CASP14 (Caspase 14). [provided by Alliance of Genome Resources, Apr 2022]

Casp14 Products(1)

mRNA Protein Name
NM_009809.5 NP_033939.1 caspase-14
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
is active in cornified envelope IDA
IDA: Inferred from direct assay
26644517 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

caspase-14

CASP-14

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01948 CASP14 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20533 Casp14 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27042 Casp14 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Casp14 NCBI NCBI:23581