2. Gene
  3. Araf - Araf proto-oncogene, serine/threonine kinase Gene

Araf - Araf proto-oncogene, serine/threonine kinase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as A-Raf; Araf1; 1200013E08Rik

Gene ID: 11836 | Gene type: protein coding

About Araf

Summary

Predicted to enable MAP kinase kinase kinase activity. Predicted to be involved in several processes, including MAPK cascade; regulation of TOR signaling; and regulation of cellular protein metabolic process. Predicted to act upstream of or within phosphorylation. Located in mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; immune system; and retina. Orthologous to human ARAF (A-Raf proto-oncogene, serine/threonine kinase). [provided by Alliance of Genome Resources, Apr 2022]

Araf Products(2)

mRNA Protein Name
NM_001159645.1 NP_001153117.1 serine/threonine-protein kinase A-Raf isoform 2
NM_009703.2 NP_033833.1 serine/threonine-protein kinase A-Raf isoform 1
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
9488663 MGI
Cellular Component GO Annotation Evidence Reference Source
located in mitochondrion IDA
IDA: Inferred from direct assay
12931191 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine/threonine-protein kinase A-Raf

A-Raf proto-oncogene serine/threonine-protein kinase

proto-oncogene A-Raf

raf-related oncogene

v-raf murine sarcoma 3611 viral oncogene homolog 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (8)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-158115 NST-628 Inhibitor 98.61% Unkown
HY-162752 Anticancer agent 250 / Unkown
HY-169869 pan-Raf/RTK inhibitor 1 Inhibitor / Unkown
HY-176305S Neurofilament, U-15N / Unkown
HY-18652A Avutometinib potassium Inhibitor / Unkown
HY-RS00886 ARAF Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18462 Araf Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24943 Araf Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Araf NCBI NCBI:369