2. Gene
  3. Ntn1 - netrin 1 Gene

Ntn1 - netrin 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as netrin-1

Gene ID: 114523 | Gene type: protein coding

About Ntn1

Summary

Predicted to enable cytokine activity. Involved in several processes, including Cdc42 protein signal transduction; positive regulation of axon extension; and substrate-dependent cell migration, cell extension. Located in extracellular matrix. Human ortholog(s) of this gene implicated in congenital mirror movement disorder. Orthologous to human NTN1 (netrin 1). [provided by Alliance of Genome Resources, Apr 2022]

Ntn1 Products(1)

mRNA Protein Name
NM_053731.3 NP_446183.2 netrin-1 precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in Cdc42 protein signal transduction IDA
IDA: Inferred from direct assay
23453953 RGD
involved in Ras protein signal transduction IDA
IDA: Inferred from direct assay
23453953 RGD
involved in positive regulation of axon extension IDA
IDA: Inferred from direct assay
23453953 RGD
involved in positive regulation of cell motility IDA
IDA: Inferred from direct assay
23453953 RGD
involved in substrate-dependent cell migration, cell extension IDA
IDA: Inferred from direct assay
23453953 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

netrin-1

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09621 NTN1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18629 Ntn1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25115 Ntn1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ntn1 NCBI NCBI:9423
Mus musculus Ntn1 NCBI NCBI:18208